Grapefruit (NAHA) |
Grapefruit juice: Beware of dangerous medication interactions
Grapefruit juice, other grapefruit products and certain other citrus fruits can interfere with several kinds of prescription medications.
Certain chemicals that grapefruit products and citrus fruits contain can interfere with the enzymes that break down (metabolize) various medications in your digestive system. As a result, more medication stays in your body. This can increase the potency of your medication to potentially dangerous levels, causing serious side effects.
This is not a complete list of grapefruit-medication interactions, so check with your doctor or pharmacist to see if your medication is affected.
Examples of grapefruit-medication interactions | |
---|---|
Type of medication | Medication name |
Anti-anxiety | Buspirone |
Anti-arrhythmia | Amiodarone (Cordarone) |
Antidepressant | Sertraline (Zoloft) |
Antihistamine | Fexofenadine (Allegra) |
Anti-retroviral | Saquinavir (Invirase), indinavir (Crixivan) |
Anti-seizure | Carbamazepine (Carbatrol, Tegretol) |
Calcium channel blocker | Nifedipine (Procardia), nimodipine (Nimotop), nisoldipine (Sular) |
Immunosuppressant | Cyclosporine (Neoral, Sandimmune), tacrolimus (Prograf), sirolimus (Rapamune) |
Statin | Simvastatin (Zocor), lovastatin (Mevacor), atorvastatin (Lipitor) |
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